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But frequent marijuana use causes inappropriate activation of CB1, which can cause inflammation and atherosclerosis, and it is associated with obesity, cancer and diabetes

Additionally, ADHD is often associated with risk-taking behaviors, and experimenting with smoking or vaping can be part of a broader pattern of sensation-seeking

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That would involve taking a group of say 6,000 people, selecting 3,000 at random and forcing them to smoke for 5 years, while forcing the other 3,000 not to smoke for 5 years, and then comparing the incidence of lung cancer in the two groups, says Donald Gillies, an emeritus professor of philosophy of science and mathematics at University College London