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Participants were assessed as being at risk of alcohol dependence or not according to their responses to the Alcohol Use Disorders Identification Test (AUDIT), which includes questions such as how often respondents had failed to do what was normally expected of them because of drinking

[12] Tobacco-specific impurities such as cotinine, nicotine-N'-oxides ( cis and trans isomers), and beta-nornicotyrine are believed to be the result of bacterial action or oxidation during the extracting of nicotine from tobacco