Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen P, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mrkve SH, Lund-Johansen M, Chalmers AJ, Bjerkvig R, Niclou SP, Gottlieb E
Microbial metabolites such as short-chain fatty acids (SCFAs), particularly butyrate, exert protective effects by enhancing regulatory T cell differentiation and intestinal barrier integrity, with butyrate treatment reducing lesion size in murine models (42)
Lu B, Solomon DH, Costenbader KH, Karlson EW
This combination also disrupts human cell viability and gut microbial composition in vitro
Why IV/IM over oral: oral glutathione has low bioavailability (much is broken down in digestion)