The Australian Therapeutic Goods Administration added AOD-9604 to its Poisons Standard under performance and image-enhancing drugs (PIEDs), and possession without a legal prescription is restricted in Australia
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Both peptides have documented immunomodulatory activity: Epitalon pineal-immune axis: melatonin is a potent immunomodulator, and melatonin restoration in aged animals is associated with improved NK cell cytotoxicity, T-cell proliferative responses, and reduced pro-inflammatory cytokine baseline (TNF-, IL-6)
"Entrez Gene: GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase)"
The copper ion may dissociate from the GHK tripeptide, and free copper ions are pro-oxidant