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NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

Standard or sample was transferred in triplicate to a 96-well plate and GSH was then derivitized by the addition of 10 mM 2,3-naphthalenedicarboxyaldehyde and the fluorescence at Ex/Em wavelength of 472/528 nm was quantified using a fluorescent plate reader (Synergy 2, BioTek)

The one-week injection interval is far more important than any meal-based timing

Here, we present ProTox-II that incorporates molecular similarity, pharmacophores, fragment propensities and machine-learning models for the prediction of various toxicity endpoints

doi: 10.7150/ijbs.96425 155 ZhangK.HuangQ.LiX.ZhaoZ.HongC.SunZ.et al