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Importantly, combination experiments in animals provided early evidence of synergy: animals treated with both a GLP-1 analogue (such as ecnoglutide, an experimental GLP-1 RA) and an amylin analogue lost markedly more weight than those treated with either agent alone, far exceeding additive expectationsbiospace.combiospace.com

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Some members say that you should be tested every 2 -4 weeks but I did not feel the full difference of a dose change for 8 weeks (although there was a very small difference in the first week) I also have to say that some sufferers do well after having RAI (but not if you have TED, which I do) or surgery - we dont always hear about the successes on this forum