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With respect to biological lipids, excess lipid intake, especially non-esterified saturated fatty acids (NEFA), leads to mitochondrial and endoplasmic reticulum (ER) stress

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The dietary intake and bioavailability of coenzyme Q10 are low and therefore it has been recommended to be administrated by supplements (Duarte-Jurado et al

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In breast cancer, it disrupts BRD4AMPK interactions, releasing AMPKmTORULK1 signaling to promote autophagosome formation and cancer cell death

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