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Online popularity has surged due to claims involving: Faster tanning Darker skin tone Reduced sun exposure needs Cosmetic appearance enhancement However, it is important to understand that Melanotan II remains controversial

Patients with pre-existing conditions including cardiovascular disease, liver disease, thyroid disorders, kidney disease, or gallbladder disease face particular uncertainty

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A meta-analysis of nine randomised trials in 591 women with PCOS found significant reductions in HOMA-IR, total cholesterol, and triglycerides, with no clear effect on luteinising hormone, total testosterone, or sex hormone binding globulin