foxo4-dri senolytic 2023 2024 study regulates endothelial cell senescence via the P53 signaling pathway ES2 rapidly destroys TP53-FOXO4 foci

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It was earlier shown, that PINK, PRKIN, MFN-1, MIEF and UCP-1 mediates mitophagy maintaining intracellular homeostasis and becoming a key point in mitochondrial quality control which was found to correlate with insulin resistance [59]

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