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Measurement of the concentration of citrate in human biofluids in patients undergoing continuous renal replacement therapy using regional citrate anticoagulation: application of a two-step enzymatic assay

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Zonulin was shown to reversibly open tight-junctions in a protease-activated receptor 2 (PAR2) and epidermal growth factor receptor (EGFR) dependent manner resulting in dislocation of ZO-1 from the tight junction (71)