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Statistical calculations were performed using Mann-Whitney U test (IBLM SPSS Statistics 21.0, IBM Corporation, Armonk, NY)

A recent phase II clinical trial in Parkinsons disease, which assessed DFP in 372 newly diagnosed, untreated PD patients over 36 weeks, revealed that DFP not only failed to improve disease symptoms but was associated with a worsening of motor and non-motor symptoms compared to placebo (Negida et al., 2024), this did not translate into clinical benefit in PD patients

Mitochondrial and inflammatory biomarkers may also provide clinical context

10.1164/ajrccm.151.6.7767513

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