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Cesarec et al., 2013

Markedly reduced PHGDH enzyme activity in the liver, muscle, and pancreas compared to the high-selenium alone group

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Contra-indications: Identifying conditions or factors that may make the use of glutathione inappropriate or contraindicated

This medication has a black box warning that patients with symptomatic heart failure that require decompensation via hospitalization have double the risk of mortality when taking this medication