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Specifically, the brains were dissected using coronal section with mandatory 2 sections according to NTP-7, Level 3 and 6, due to neuroanatomic subsites present in certain brain sections [51]

A STAT5b binding site has been characterized in the IGF-I gene promoter region, which mediates GH-stimulated IGF-I gene activation (54)

These pathways converge to create a state of chronic OS that further exacerbates insulin resistance and -cell dysfunction, and plasma F2-isoprostanes (markers of lipid peroxidation) correlate strongly with HbA1c levels (Tang et al., 2018)

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40, 163221.10.1016/0301-0082(93)90022-K 101 NelsonC