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Simply replace them when empty

Those particles stick to airway mucus and can stain it brown or black

That, in turn, can lead to chronic inflammation, which has been linked to both the development and spread of certain types of cancer

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Roles of UPS in the hippo signaling pathway The evolutionarily conserved Hippo signaling pathway, originally discovered in Drosophila genetic studies two decades ago, orchestrates tissue homeostasis and organ size control through the precise regulation of balance between proliferation and apoptosis (Fu et al