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To mimic the stroke population, we further analyzed patients 50 years and older, which consisted of 59 subjects with an average age of 68.0 and median CHA2DS2-VASc score of 3

In this context, L* represents brightness, a* represents redness, and b* represents yellowness

The cardiovascular effects of tirzepatide were evaluated in the large SURPASS-CVOT trial, which compared tirzepatide directly with dulaglutide (Trulicity) a GLP-1 medication already proven to reduce cardiovascular events

Peptide therapy is provided only after medical consultation by a licensed provider

One intriguing recent discovery is that gut microbes can produce small amounts of ammonia and other compounds that affect brain metabolism: a 2025 study showed that manipulating the gut microbiome altered brain amino acid levels and stress susceptibility in mice, partly via microbe-derived ammonia affecting neurotransmitter cycling [88]