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This could suggest an overactive Gln-Glu cycle in adults with ASD, which may represent either a manifestation of, or a compensatory response to, dysregulated excitatory neurotransmission implicated in the pathophysiology of ASD

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doi:10.1016/j.pediatrneurol.2005.03.014 Horvath K, Perman JA (2002) Autistic disorder and gastrointestinal disease