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[3] Sikiric P, Udovicic M, Barisic, I et al

FIGURE 2 The role of oxidative stress in articular cartilage degeneration Biochemical analysis of degenerative cartilage from patients with OA showed that there was a pathological relationship between the downregulation of SOD2 and cartilage degeneration in the progression of OA, suggesting that the redox balance centred on SOD2 in mitochondria plays a central role in the pathogenesis of KOA (Ruiz-Romero et al., 2009

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Laviano A, Meguid MM, Guijarro A, Muscarioti M, Cascino A, Preziosa I, et al

La proteccin del cartlago sigue el mismo camino: menos estrs oxidativo significa una disminucin de la actividad de las metaloproteinasas de la matriz, lo que detiene la erosin