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L-Citrulline accelerates ammonia clearance, decreases muscle pH that occurs during severe exertion

Some researchers report reliable potency up to 45 days, but 28 days is the conservative window supported by stability data

The inability of affected cell to clear nonfunctionally associated PD-specific Syn variants with endogenous proteins has a detrimental effect on postmitotic neurons, a phenomenon previously reported in prion-infected cells 82

Most studies involve small participant numbers, short follow-up periods, and lack robust placebo controls, limiting the strength of conclusions