Indeed, other conditions that slow intracellular metabolism, such as inhibition of mTOR signaling or deprivation of certain amino acids, also appear to increase resistance to ferroptosis through GSH-conserving mechanisms that may be unrelated to nucleotide synthesis (Conlon et al, 2021)
28, 30 Colchicine plasma concentrations can be doubled by concomitant CYP3A4 inhibitor use and quadrupled by concomitant P-glycoprotein inhibitor use
336 Enoyl coenzyme A hydratase 1 helps alleviates MASH in mice by suppressing hepatic ferroptosis
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