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Differences in the cortisol response between our data and the previous study 47 are expected since cortisol accumulates in urine over time and the cortisol levels in excreted urine are therefore dependent on the frequency of urination

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Identification of blood metabolic biomarkers associated with diabetic distal symmetric sensorimotor polyneuropathy in patients with type 2 diabetes mellitus

However, long-term use of topical corticosteroids can result in adverse effects, including skin atrophy, particularly in sensitive areas