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Therefore, we hypothesized that sertraline treatment in combination with RT would not only target the tumor by SHMT inhibition to enhance sensitivity of NSCLC tumors to radiation in vivo but may also release the brake on the immune system

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Proposed modifications to the new technology add-on payment application eligibility requirements for technologies that are not already Food and Drug Administration (FDA) market authorized to require such applicants to have a complete and active FDA market authorization request at the time of new technology add-on payment application submission, to provide documentation of FDA acceptance or filing, and to move the FDA marketing authorization deadline from July 1 to May 1, beginning with applications for FY 2025 (as discussed in section II.E.8

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Bucholtz N., Demuth I