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Intraperitoneal administration, used primarily in animal studies for convenience, results in faster absorption through the highly vascularized peritoneal membrane, shortening the dihexa half life to one to two hours and producing higher peak plasma concentrations

doi: 10.1096/fj.12-220202

Muscle & Tissue Signaling Research: Examining cellular responses related to structural protein signaling, repair coordination, and growth-factor pathway activation

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However, it varies on the treatment plan and skin goal