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[DOI] [PMC free article] [PubMed] [Google Scholar] 198.Biao M., Wsik A

The only untoward consequence of alkaptonuria is ochronosis (bluish-black discoloration of the tissues) and arthritis of indeterminate etiology

Despite advancements in treatment, the prognosis for many patients remains poor, highlighting the urgent need for integrative and preventive approaches

Because in Ica the dunes of its enormous deserts protect the cultural and historical legacy of ancient civilizations, as well as the location of an oasis like the Huacachina