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Moreover, hesperetin and hesperidin are reported to directly suppress viral replication in other pathogens such as RSV, zika virus (ZIKV), chikungunya virus (CHIKV), suggesting them as potential broad-spectrum antiviral agents with multi-target mechanisms (302, 303)

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The overall genome completeness of SAGs with 5% contamination, which would be caused either by contaminating extracellular DNA or by multiple cells being encapsulated in a single AGM, were binned into each bacterial species using metaWRAP 31 , although discrimination between contaminating DNA and DNA from captured multiple cells was difficult