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Comparing the schistosomicidal activity against juvenile worms with that of PZQ reported in previous in vivo studies 61 , the inhibitors reported herein show superior schistosomicidal activity to PZQ at the worm developmental stage in mice

References Chan CS, Van Voorhees AS, Lebwohl MG, Korman NJ, Young M, et al

Acknowledgements The authors would like to thank the experimental apparatus and technical support provided by the Key Laboratory for Metabolic Diseases in Chinese Medicine, Nanjing University of Chinese Medicine

Some research suggests that the glucagon component may have muscle-sparing properties compared to pure GLP-1 agonists, but this requires further study

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