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But with vaping, people can do it constantly, says Patricia Folan, RN, the director of the Northwell Health Center for Tobacco Control in Great Neck, New York

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Minor contributions to drug metabolism have been observed in vitro from CYP1A1, CYP2C8, and CYP2C18, though these enzymes are less relevant in vivo due to their lower hepatic expression compared to CYP3A4 (Shimada et al., 1994)