However, the outcomes of ROS-protein interactions are complex and dependent on several contextual factors including the concentration and type of ROS, the cell type, and the specific signaling pathways that are altered
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Vitamin E, a lipid-soluble antioxidant, localizes to erythrocyte membranes, scavenges lipid peroxyl radicals, and maintains membrane fluidity and integrity, which mitigates ROS-induced membrane damage and Ca 2+ permeation
These proteins included extracellular vesicle interleukin-2 (EV IL2) and cathelicidin antimicrobial protein (CAMP) which were elevated, while immunoglobulin lambda variable 1-47 (IGLV1-47), cartilage acidic protein 1 (CRTAC1), leucine-rich alpha-2-glycoprotein 1 (LRG1), insulin-like growth factor 1 (IGF1), and tubulin alpha-1 (TUBA1) were decreased relative to healthy controls