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Secondary effects of photon absorption include increases in ATP, a brief burst of reactive oxygen species, an increase in nitric oxide, and modulation of calcium levels

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The therapeutic effects of SAM are associated with the downregulation of the ERK1/2 and STAT3 signaling pathways, both of which are involved in the survival, proliferation, migration, and invasion of cancer cells

Relative gene expression levels were analyzed according to the comparative 2 CT method (27)