When the stores are depleted, we encounter symptoms such as fatigue, weakening of the immune system, and the skin losing its former glow and becoming dull
Annu Rev Biochem (2007) 76:70122
Peptides seem to be just about everywhere lately
One possible scenario is the metabolic cofactor NADPH, which is known to be required not only for lipid synthesis but also for the function of antioxidant reductases, such as glutathione reductase (GSR) and thioredoxin reductase (TXNRD) 86
For this reason, genetic mosaicism is currently the most accepted theory to explain this condition, though it has not yet been genetically confirmed.94 New pathogenic pathways and potential new therapeutic targets The pathogenesis of vitiligo is multifactorial, involving a complex interaction between genetic predisposition and various environmental factors, oxidative stress, and autoimmune responses