glutathione sigma L-Glutathione reduced, 70-18-8, G4251, Sigma-Aldrich The three amino acids present in GSH are glycine Glutathione | Sigma-Aldrich

It acts as the ultimate electron donor for the glutaredoxin system, which activates ribonucleotide reductase (RNR) , the rate-limiting enzyme responsible for converting ribonucleotides into the deoxyribonucleotides (dNTPs) needed for DNA replication

Trends Microbiol 13:111118 Averyanov AA, Lapikova VP (1990) Activated oxygen as a possible factor in the autoinhibition of spore germination of the fungus Pyricularia oryzae

It retains full functionality for 24 months at room temperature, 2 to 8C, or -5 to -30C for convenient storage and handling

A variety of anticancer drugs based on these principles have been synthesized in efforts to improve their therapeutic indices and reverse tumor resistance

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