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Dirty cage Dirty cages were placed beneath the cages of IIRI + MET mice

The duration of therapy for intranasal treatment is tested, commonly used, and deemed safe for at least 18 months

For example, genetically modified Lactobacillus strains have been explored as mucosal antigen delivery platforms, demonstrating the capacity to elicit both local IgA and systemic immune responses in experimental livestock models 209

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M.tb manipulates cAMP signaling pathways within infected macrophages, thereby influencing its survival [107]