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Interestingly, the treatment demonstrated dose-dependent therapeutic effects, with moderate dosages proving more effective than high doses (1,000 mg/kg), possibly due to pharmacodynamic principles, where excessive concentrations saturate biological pathways and diminish therapeutic outcomes (Tyagi et al., 2025

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The study's lead author is Ying Lai, PhD, a former postdoctoral scholar in Brunger's lab and now an assistant professor at Sichuan University in Chengdu, China