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El estudio no encontr diferencias significativas en efectos secundarios sistmicos entre rutas, pero not que las reacciones en sitio de inyeccin fueron la causa principal de discontinuacin del tratamiento (3% de usuarios inyectables versus 1% de usuarios orales discontinuando debido a malestar GI)

These receptors sit in the area postrema and the nucleus of the solitary tract, regions that regulate satiety, gastric emptying, and food intake

PMID 20607069

This study reveals why individuals lacking pigmentation potentially vulnerable to retinal damage

They make pancreatic beta cells produce insulin, stop glucagon from being released, slow the emptying of the stomach, and lower appetite through paths in the central nervous system