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Dahlke et al., 2021), and is consistent with the idea of a primary cytodegeneration as the initiator of the disease

However, hemolysis, which can be considered as necrosis of erythrocytes, belongs to the so-called ACD modalities, indicating that this cell death occurs in response to physical or mechanical damage to RBCs and lacks signaling pathways [4]

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It is used in laboratory studies exploring tissue repair, cellular signaling, and regeneration pathways

Endoplasmic reticulum-mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis