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When using dilute acetic acid (0.1% v/v) as a solvent, it can improve initial solubilization of certain peptide batches, but the solution pH should be adjusted to near-physiological range before administration to avoid tissue irritation at the injection site in animal models

The cytotoxicity of epsilon toxin from clostridium perfringens on lymphocytes is mediated by mal protein expression

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10.1038/nature05859 150 YangW

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