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This cortisol-neutral profile is important because elevated cortisol is associated with increased appetite (particularly for high-calorie foods), abdominal fat accumulation, and metabolic complications

Bacteriostatic water is more universally compatible

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Rather than acting through a single mechanism, this peptide appears to coordinate multiple healing processes simultaneously, which may explain its consistent effectiveness across different wound types and tissue locations

This simplified the trial design but raises legitimate questions about whether weight-based dosing might improve outcomes