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[74] Dosage The first factor, dosage, has been a truism since ancient times, or at least since Paracelsus who said, "Dose makes the poison." Some compounds are beneficial or pleasurable when consumed in small amounts, but harmful, deadly, or evoke discomfort in higher doses

Historically, these cases were emblematic of a bygone era when smoking was not only socially acceptable b In contemporary times, as societal attitudes towards smoking have shifted and health concerns have come to the forefront, the point of cigarette cases has evolved

Owners of gas stations and other small businesses said the ban could force them to lay-off people

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If yes, its time to reconsider