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Harvesting during this period maximizes nicotine content and leaf quality

Before the 1964 Surgeon General's report, significant scientific work was being conducted in other countries linking smoking with major health effects

One firm submitted information on more than 4 million tobacco products within a single submission

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Acknowledgements This study was supported by the National Institute on Drug Abuse (ALB (R01 DA20872)), the Tobacco-Related Disease Research Program (ALB (19XT-0135)), and the Department of Veterans Affairs, Office of Research and Development (CSR&D Merit Review Award I01 CX000412 (ALB))