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Paans exact history in South Asia is unknown
Widespread upregulation of nAChRs, likely related to receptor desensitization from nicotine exposure, has been observed among smokers [70, 71] and, conversely, smoking cessation associated with decreases in regional nAChR densities [72]
de Benedictis-Kessner, J., Lee, D
British American Tobacco said it is clear cigarettes pose serious health risks but added it does not believe that a generational sales ban will have the desired impact given the serious unintended consequences that are likely to follow. For those adults who would otherwise continue to smoke or start smoking, we believe they should be able to make better choices by opting for smokeless alternatives instead of cigarettes, a spokesman added
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