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They identified the iron storage protein, ferritin light chain 1 (FTL1), as a pro-ageing neuronal factor: its overexpression in the hippocampus of young mice accelerated cognitive decline, whereas knockdown in aged mice preserved synaptic integrity and prevented cognitive deterioration

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Cysteine, which can be derived from the sulfur of methionine through the TSP, seems to undergo conversion into taurine via the cysteine sulfinate pathway and serves as an osmolyte, a neuromodulator, an immunomodulator, and an antioxidant (22)