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They risk developing "skin pathologies such as acne and conditions that leave scars and black spots that are very hard to treat." Her observations were echoed by Grace Nkoro, a dermatologist at the Gynaeco-Obstetric Hospital in Cameroon

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Although different TLRs recognize distinct ligands, all TLRs share a conserved cytoplasmic domain named Toll/interleukin (IL)-1 receptor (TIR) domain, which mediates downstream signaling by recruiting specific adaptor proteins, including TIR domain-containing adaptor molecules to receptors

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