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Search strategy The PubMed, Scopus, and Web of Science (WoS) databases were searched using four combinations of Medical Subject Headings (MeSH) keywords (presented in Table 1 in the Results section)

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In the United States alone, hair loss is a significant concern, affecting 56 million individuals (35 million men and 21 million women) [1, 2]

Drugs in this class, also referred to as coxibs, COX-2-specific inhibitors, COX-2-selective NSAIDs or COX-1-sparing NSAIDs, exhibit high potency and slow dissociation from the COX-2 active site, a property conferred by their extended side chains that occupy the hydrophobic channel of the enzyme

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