Experimental data suggest a possible reduction in apoptotic signaling proteins and an increase in survival-related markers, hinting at a protective or growth-supportive role in cultured cells
Gee is Medical Director of InfusaLounge Integrative & Functional Medicine
Other groups who may benefit include: Patients following gastric surgery (gastrectomy, bariatric procedures) where intrinsic factor production or absorption sites are compromised Individuals with malabsorption disorders such as Crohn's disease, coeliac disease, or chronic pancreatitis Strict vegans and vegetarians with dietary insufficiency, though oral supplementation is usually tried first Elderly patients with atrophic gastritis or reduced gastric acid production Patients on long-term metformin or proton pump inhibitors, which can impair B12 absorption Individuals with nitrous oxide exposure (recreational or medical), which can cause functional B12 deficiency Diagnosis typically involves serum B12 measurement, with levels below approximately 148 pmol/L (though thresholds vary between laboratories) generally indicating deficiency
The study concluded that B12 deficiency disrupts catecholamine degradation and sympathetic nervous system function, directly contributing to orthostatic intolerance
While macronutrients carbs, fats, and proteins are the three basic components of our diet, micronutrients are the vitamins and minerals that are vital to our well-being
