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J Nutr 115:399410 Zapara TA, Simonova OG, Zharkikh AA et al (2004) Seasonal differences and protection by creatine or arginine pretreatment in ischemia of mammalian and molluscan neurons in vitro

4.1.1 Core cell types and their roles As the main inflammatory cells infiltrating the airways, neutrophils disrupt the integrity of the airway epithelium by releasing elastase and matrix metalloproteinases (MMP-9), while secreting IL-8 and TNF- to amplify the inflammatory cascade (24, 25)

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Meanwhile, photo-oxidative stress activated the biosynthesis of enzymes to counteract intracellular 2 NP and expel 1 NF