Whitfield K
Wadhwa R, Wang X, Baladandayuthapani V, Liu B, Shiozaki H, Shimodaira Y, Lin Q, Elimova E, Hofstetter WL, Swisher SG , Rice DC, Maru DM, Kalhor N, Bhutani MS, Weston B, Lee JH, Skinner HD, Scott AW, Kaya DM, Harada K, Berry D, Song S, Ajani JA
Several neurocognitive peptides have shown memory and cognition effects in animal models and small human studies, primarily through pathways involving BDNF (brain-derived neurotrophic factor), nerve growth factor, and synaptic plasticity
Thus, not only the size but also the charge and shape of the glutathionylated substrate are relevant with GS in GSSG being the optimal leaving group in accordance with a 2nd glutathione-interaction site (Fig
246,247 Apart from acetylation, lactate alters the anaphase-promoting complex (APC/C) by directly blocking the Small Ubiquitin-like Modifier protease (SUMO protease) sentrin/SUMO-specific protease 1 (SENP1) and stabilizing SUMOylation at two specific residues on APC4