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Does AOD-9604 affect blood sugar or IGF-1

This could potentially limit its use in human medicine

Importantly, AOD9604 achieved these effects without activating the growth-promoting pathways that full-length growth hormone uses, which is why it doesnt cause the unwanted side effects of growth hormone therapy such as insulin resistance or abnormal growth

When this is the case, one shot wont be nearly enough, because it doesnt last long

More importantly, my co-author, Anna Thalacker-Mercer from the University of Alabama at Birmingham, wondered if B12 supplementation in aged mice would improve muscle mitochondrial function and it did. Previous research has largely concentrated on the visible consequences of B12 deficiency, such as megaloblastic anemia, neuropathy, and cognitive decline, rather than examining the underlying biological mechanisms