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Active immunization against riboflavin carrier protein results in peri-implantation embryonic loss leading to pregnancy termination in rats: use of alternate adjuvants

Many genes are known to be regulated by HNF-4 including those encoding HNF-1, PPAR, insulin, glucose-6-phosphatase, GLUT2, the liver pyruvate kinase isoform (L-PK which is also expressed in the pancreas), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), aldolase B, and uncoupling protein 2, UCP2

That's great for durability and terrible for recovery