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DAMPs released from ferroptotic cellssuch as lipid oxidation products [hydroxynonenal (4-HNE) and oxidized phospholipids (oxPLs)], HMGB1, and dsDNAactivate the TLR4-MyD88-NF-B and cGAS-STING pathways, driving the production of proinflammatory cytokines and type I interferons (Wang et al., 2019

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ARA-290 Peptide and Retinal Ischemia A recent study (6) has suggested that ARA-290 may have the potential to protect the endothelial blood vessels and possibly thereby combat retinal ischemia in models of ischemic retinopathies