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By mediating cystine uptake, SLC7A11 governs rate-limiting GSH production

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5 Specific enzymes in intracellular lysosomes or tumor microenvironments can selectively break the linker, for example, proteases in lysosomes hydrolyzing peptide bonds contained in dipeptide or tetrapeptide linkers, glycosidases hydrolyzing -glucuronides and -galactosides, phosphatases hydrolyzing phosphoesters and pyrophosphates, and sulfatases hydrolyzing sulfates

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10.1016/j.psychres.2020.113471 CrossRef Google Scholar View reference in article 3

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"Better" depends on individual response, tolerance, medical history, and specific metabolic goals

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