Growth hormone-releasing peptide 2 (GHRP-2) has shown reduced M1 macrophage polarization at the tendon-bone interface in rat models, potentially improving the healing environment after surgical repair
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In vivo rodent studies have investigated BPC-157 across gastrointestinal ulcer models, tendon and ligament transection models, and peripheral nerve injury paradigms, with research examining angiogenesis and new-vessel and granulation-tissue formation in both gastrointestinal mucosa and musculoskeletal tissue [3][4], alongside collagen deposition kinetics and, in a separate body of central nervous system work, dopaminergic and serotonergic system dynamics, following both systemic and local administration